Pruritus: Management Algorithms and Experimental Therapies

Management and treatment of pruritus.

Pruritus, or itch, is a common sensation that causes a person to want to scratch. It is a complex process that may negatively impact quality of life and commonly occurs with skin disorders such as atopic dermatitis and urticaria. It could also be a symptom related to an underlying disease process such as cholestasis or hyperthyroidism, or simply be caused by dry skin, especially in the cold, wi...

Topical aprepitant in clinical and experimental pruritus.

Comment. While privately insured patients enjoyed a 91% acceptance rate and relatively shorter wait times, the publicly insured patients faced significantly lower acceptance rates and longer appointment wait times. Despite making up less than 20% of the workforce, academic dermatologists provide most of the care for Medicaid patients in Ohio. Not only does this limit access to care for the publ...

Preoperative Evaluation and Management of Patients Receiving Biologic Therapies

The preoperative care of patients undergoing orthopedic surgery and treated with biologic agents is of great significance.Perioperative use of biologic agents could lead to such complications as infection and delayed postoperative woundhealing. This narrative review aimed to evaluate the current information on the use of biologic agents in patientsundergoing orthopedic surgery...

Uremic Pruritus; Its Prevalence, Pathophysiology and Management

Hypertension and experimental stroke therapies.

UNLABELLED Hypertension is an established target for long-term stroke prevention but procedures for management of hypertension in acute stroke are less certain. Here, we analyze basic science data to examine the impact of hypertension on candidate stroke therapies and of anti-hypertensive treatments on stroke outcome. METHODS Data were pooled from 3,288 acute ischemic stroke experiments (47,8...